Impact of FHIT loss on the translation of cancer-associated mRNAs

BACKGROUND: FHIT is a genome caretaker/tumor suppressor that is silenced in >50% of cancers. Although it was identified more than 20 years ago, questions remain as to how FHIT loss contributes to cancer, and conversely, how FHIT acts to maintain genome integrity and suppress malignancy. Fhit belo...

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Detalles Bibliográficos
Autores principales: Kiss, Daniel L., Baez, William, Huebner, Kay, Bundschuh, Ralf, Schoenberg, Daniel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745650/
https://www.ncbi.nlm.nih.gov/pubmed/29282095
http://dx.doi.org/10.1186/s12943-017-0749-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745650/
https://www.ncbi.nlm.nih.gov/pubmed/29282095
http://dx.doi.org/10.1186/s12943-017-0749-x

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