Mesenchymal Stem Cells Protect Nucleus Pulposus Cells from Compression-Induced Apoptosis by Inhibiting the Mitochondrial Pathway

OBJECTIVE: Excessive apoptosis of nucleus pulposus cells (NPCs) induced by various stresses, including compression, contributes to the development of intervertebral disc degeneration (IVDD). Mesenchymal stem cells (MSCs) can benefit the regeneration of NPCs and delay IVDD, but the underlying molecul...

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Detalles Bibliográficos
Autores principales: Chen, Sheng, Zhao, Lei, Deng, Xiangyu, Shi, Deyao, Wu, Fashuai, Liang, Hang, Huang, Donghua, Shao, Zengwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745742/
https://www.ncbi.nlm.nih.gov/pubmed/29387092
http://dx.doi.org/10.1155/2017/9843120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745742/
https://www.ncbi.nlm.nih.gov/pubmed/29387092
http://dx.doi.org/10.1155/2017/9843120

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