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Modulation of Multidrug Resistance Gene Expression by Coumarin Derivatives in Human Leukemic Cells
The presence of multidrug resistance (MDR) in tumor cells is considered as the major cause of failure of cancer chemotherapy. The mechanism responsible for the phenomenon of multidrug resistance is explained, among others, as overexpression of membrane transporters primarily from the ABC family whic...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745744/ https://www.ncbi.nlm.nih.gov/pubmed/29387293 http://dx.doi.org/10.1155/2017/5647281 |