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Modulation of Multidrug Resistance Gene Expression by Coumarin Derivatives in Human Leukemic Cells

The presence of multidrug resistance (MDR) in tumor cells is considered as the major cause of failure of cancer chemotherapy. The mechanism responsible for the phenomenon of multidrug resistance is explained, among others, as overexpression of membrane transporters primarily from the ABC family whic...

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Detalles Bibliográficos
Autores principales: Kubrak, Tomasz, Bogucka-Kocka, Anna, Komsta, Łukasz, Załuski, Daniel, Bogucki, Jacek, Galkowski, Dariusz, Kaczmarczyk, Robert, Feldo, Marcin, Cioch, Maria, Kocki, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745744/
https://www.ncbi.nlm.nih.gov/pubmed/29387293
http://dx.doi.org/10.1155/2017/5647281