N,N-disubstituted azines attenuate LPS-mediated neuroinflammation in microglia and neuronal apoptosis via inhibiting MAPK signaling pathways

BACKGROUND: Activated microglia interact with astrocytes and neuronal cells to induce neuroinflammation, which can contribute to the pathogenesis and progression of Alzheimer’s and Parkinson’s disease. To identify the most effective anti-neuroinflammatory agent, we designed and synthesized a family...

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Detalles Bibliográficos
Autores principales: Subedi, Lalita, Kwon, Oh Wook, Pak, Chaeho, Lee, Goeun, Lee, Kangwoo, Kim, Hakwon, Kim, Sun Yeou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745756/
https://www.ncbi.nlm.nih.gov/pubmed/29281977
http://dx.doi.org/10.1186/s12868-017-0399-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745756/
https://www.ncbi.nlm.nih.gov/pubmed/29281977
http://dx.doi.org/10.1186/s12868-017-0399-3

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