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Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model

BACKGROUND: Ulcerative colitis (UC) is a highly progressive inflammatory disease that requires the interaction of epithelial, immune, endothelial and muscle cells and fibroblasts. Previous studies suggested two inflammatory conditions in UC-patients: ‘acute’ and ‘remodeling’ and that the design of a...

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Detalles Bibliográficos
Autores principales: Jodeleit, Henrika, Palamides, Pia, Beigel, Florian, Mueller, Thomas, Wolf, Eckhard, Siebeck, Matthias, Gropp, Roswitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745765/
https://www.ncbi.nlm.nih.gov/pubmed/29282132
http://dx.doi.org/10.1186/s12967-017-1368-4