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Activation of the Akt/mTOR signaling pathway: a potential response to long-term neuronal loss in the hippocampus after sepsis
Survivors of sepsis may suffer chronic cognitive impairment as a long-term sequela. However, the precise mechanisms of cognitive dysfunction after sepsis are not well understood. We employed the cecal ligation-and-puncture-induced septic mouse model. We observed elevated phosphorylation of Akt, mamm...
Autores principales: | Guo, Jia-nan, Tian, Lin-yu, Liu, Wen-yu, Mu, Jie, Zhou, Dong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745837/ https://www.ncbi.nlm.nih.gov/pubmed/29239329 http://dx.doi.org/10.4103/1673-5374.219044 |
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