Can testing clinical significance reduce false positive rates in randomized controlled trials? A snap review

OBJECTIVE: The use of minimum clinically important difference in the hypothesis formulation for superiority trials is similar in principle to the concept of non-inferiority or equivalence trial. However, most clinical trials are analysed testing zero clinical difference. Since the minimum clinically...

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Detalles Bibliográficos
Autores principales: Bigirumurame, Theophile, Kasim, Adetayo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745896/
https://www.ncbi.nlm.nih.gov/pubmed/29282120
http://dx.doi.org/10.1186/s13104-017-3117-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745896/
https://www.ncbi.nlm.nih.gov/pubmed/29282120
http://dx.doi.org/10.1186/s13104-017-3117-4

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