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Can testing clinical significance reduce false positive rates in randomized controlled trials? A snap review

OBJECTIVE: The use of minimum clinically important difference in the hypothesis formulation for superiority trials is similar in principle to the concept of non-inferiority or equivalence trial. However, most clinical trials are analysed testing zero clinical difference. Since the minimum clinically...

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Detalles Bibliográficos
Autores principales:	Bigirumurame, Theophile, Kasim, Adetayo S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745896/ https://www.ncbi.nlm.nih.gov/pubmed/29282120 http://dx.doi.org/10.1186/s13104-017-3117-4

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