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Translational control of a human CDKN1A mRNA splice variant regulates the fate of UVB-irradiated human keratinocytes

In response to sublethal ultraviolet B (UVB) irradiation, human keratinocytes transiently block progression of the cell cycle to allow ample time for DNA repair and cell fate determination. These cellular activities are important for avoiding the initiation of carcinogenesis in skin. Central to thes...

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Detalles Bibliográficos
Autores principales: Collier, Ann E., Spandau, Dan F., Wek, Ronald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746064/
https://www.ncbi.nlm.nih.gov/pubmed/29118075
http://dx.doi.org/10.1091/mbc.E17-06-0362