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A novel thiazolidinediones ATZD2 rescues memory deficits in a rat model of type 2 diabetes through antioxidant and antiinflammation

Type 2 diabetes (T2DM) has been associated with learning and memory impairment; however, drugs for diabetes could not prevent the development of cognitive decline in T2DM patients. In the present study, compounds derived from thiazolidinediones (TZD), a PPAR-γ agonist, were synthesized by conjunctin...

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Detalles Bibliográficos
Autores principales: Wang, Xuan-Kang, Sun, Ting, Li, Yu-Jiao, Wang, Yu-Hong, Li, Yan-Jiao, Yang, Liu-Di, Feng, Dan, Zhao, Ming-Gao, Wu, Yu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746076/
https://www.ncbi.nlm.nih.gov/pubmed/29296174
http://dx.doi.org/10.18632/oncotarget.22467