Cargando…

A novel thiazolidinediones ATZD2 rescues memory deficits in a rat model of type 2 diabetes through antioxidant and antiinflammation

Type 2 diabetes (T2DM) has been associated with learning and memory impairment; however, drugs for diabetes could not prevent the development of cognitive decline in T2DM patients. In the present study, compounds derived from thiazolidinediones (TZD), a PPAR-γ agonist, were synthesized by conjunctin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xuan-Kang, Sun, Ting, Li, Yu-Jiao, Wang, Yu-Hong, Li, Yan-Jiao, Yang, Liu-Di, Feng, Dan, Zhao, Ming-Gao, Wu, Yu-Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746076/ https://www.ncbi.nlm.nih.gov/pubmed/29296174 http://dx.doi.org/10.18632/oncotarget.22467

Ejemplares similares

Antiinflammation Derived Suzuki-Coupled Fenbufens as COX-2 Inhibitors: Minilibrary Construction and Bioassay
por: Farn, Shiou-Shiow, et al.
Publicado: (2022)

Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications
por: Li, Danyang, et al.
Publicado: (2022)

The role of inflammation and antiinflammation therapies in keratoconjunctivitis sicca
por: Gumus, Koray, et al.
Publicado: (2009)

Establishment and Evaluation of Biotechnological Platform for Screening Health Food with Antiinflammation Ability
por: Hsieh, Wang-Ju, et al.
Publicado: (2012)

In Vitro Antioxidant, Antiinflammation, and Anticancer Activities and Anthraquinone Content from Rumex crispus Root Extract and Fractions
por: Eom, Taekil, et al.
Publicado: (2020)

Therapeutic Potential of Oridonin and Its Analogs: From Anticancer and Antiinflammation to Neuroprotection
por: Xu, Jimin, et al.
Publicado: (2018)

Multitarget effects of Korean Red Ginseng in animal model of Parkinson's disease: antiapoptosis, antioxidant, antiinflammation, and maintenance of blood–brain barrier integrity
por: Choi, Jong Hee, et al.
Publicado: (2018)

Kaempferol Improves Lung Ischemia-Reperfusion Injury via Antiinflammation and Antioxidative Stress Regulated by SIRT1/HMGB1/NF-κB Axis
por: Yang, Chunli, et al.
Publicado: (2020)

Silencing [Formula: see text] Rescues Tau Pathologies and Memory Deficits through Rescuing PP2A and Inhibiting GSK-3β Signaling in Human Tau Transgenic Mice
por: Zhang, Yao, et al.
Publicado: (2014)

Cyclic Stretch Facilitates Myogenesis in C2C12 Myoblasts and Rescues Thiazolidinedione-Inhibited Myotube Formation
por: Chang, Ya-Ju, et al.
Publicado: (2016)

Thiazolidinediones lower the risk of pneumonia in patients with type 2 diabetes
por: Yen, Fu-Shun, et al.
Publicado: (2023)

Gad67 haploinsufficiency reduces amyloid pathology and rescues olfactory memory deficits in a mouse model of Alzheimer’s disease
por: Wang, Yue, et al.
Publicado: (2017)

Type 2 Diabetes: Uses of thiazolidinediones and insulin
por: T. Bloomgarden, Zachary
Publicado: (2011)

Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease
por: O'Connor, Margaret, et al.
Publicado: (2020)

Thiazolidinedione Derivatives: In Silico, In Vitro, In Vivo, Antioxidant and Anti-Diabetic Evaluation
por: Sameeh, Manal Y., et al.
Publicado: (2022)

Thiazolidinedione derivatives as novel GPR120 agonists for the treatment of type 2 diabetes
por: Wang, Xuekun, et al.
Publicado: (2022)

Chemotherapy and Chemoprevention by Thiazolidinediones
por: Fröhlich, Eleonore, et al.
Publicado: (2015)

Thiazolidinediones and bone fractures
por: Kaku, Kohei, et al.
Publicado: (2011)

Thiazolidinediones and Edema: Recent Advances in the Pathogenesis of Thiazolidinediones-Induced Renal Sodium Retention
por: Horita, Shoko, et al.
Publicado: (2015)

Thiazolidinedione Use in Individuals With Type 2 Diabetes and Chronic Obstructive Pulmonary Disease
por: Yen, Fu-Shun, et al.
Publicado: (2021)

Redefining the role of thiazolidinediones in the management of type 2 diabetes
por: Barnett, Anthony H
Publicado: (2009)

Recent Pharmacological Developments on Rhodanines and 2,4-Thiazolidinediones
por: Bhatti, Ravinder Singh, et al.
Publicado: (2013)

Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease
por: Hou, Ke, et al.
Publicado: (2020)

Discovery Potent of Thiazolidinedione Derivatives as Antioxidant, α-Amylase Inhibitor, and Antidiabetic Agent
por: Sameeh, Manal Y., et al.
Publicado: (2021)

Docosahexaenoic Acid Rescues Synaptogenesis Impairment and Long-Term Memory Deficits Caused by Postnatal Multiple Sevoflurane Exposures
por: Tao, Guorong, et al.
Publicado: (2016)

Thiazolidinediones: the Forgotten Diabetes Medications
por: Lebovitz, Harold E.
Publicado: (2019)

Glycemic Control with Thiazolidinedione Is Associated with Fracture of T2DM Patients
por: Chen, Hsin-Hung, et al.
Publicado: (2015)

Indole and 2,4-Thiazolidinedione conjugates as potential anticancer modulators
por: Corigliano, Domenica M., et al.
Publicado: (2018)

An Update on the Current and Emerging Use of Thiazolidinediones for Type 2 Diabetes
por: Giglio, Rosaria Vincenza, et al.
Publicado: (2022)

Liver‐related long‐term outcomes of thiazolidinedione use in persons with type 2 diabetes
por: Yen, Fu‐Shun, et al.
Publicado: (2020)

Cooperative impact of thiazolidinedione and fatty acid synthase on human osteogenesis
por: Chen, Ching-Yun, et al.
Publicado: (2019)

Donepezil Rescues Spatial Learning and Memory Deficits following Traumatic Brain Injury Independent of Its Effects on Neurogenesis
por: Yu, Tzong-Shiue, et al.
Publicado: (2015)

Hippocampal Network Oscillations Rescue Memory Consolidation Deficits Caused by Sleep Loss
por: Ognjanovski, Nicolette, et al.
Publicado: (2018)

Modulation of KDM1A with vafidemstat rescues memory deficit and behavioral alterations
por: Maes, Tamara, et al.
Publicado: (2020)

Facilitation of axon regeneration by enhancing mitochondrial transport and rescuing energy deficits
por: Zhou, Bing, et al.
Publicado: (2016)

Treatment update: thiazolidinediones in combination with metformin for the treatment of type 2 diabetes
por: Stafford, John M, et al.
Publicado: (2007)

Synthesis of new pyrazolyl-2, 4-thiazolidinediones as antibacterial and antifungal agents
por: Aneja, Deepak K, et al.
Publicado: (2011)

Lobeglitazone: A Novel Thiazolidinedione for the Management of Type 2 Diabetes Mellitus
por: Bae, Jaehyun, et al.
Publicado: (2021)

Thiazolidinedione induced thyroid associated orbitopathy
por: Lee, Seongmu, et al.
Publicado: (2007)

Risk of Fracture with Thiazolidinediones: Disease or Drugs?
por: Bazelier, Marloes T., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2vvje6j4vodoh2c468ve628pem