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3-Methyladenine ameliorates liver fibrosis through autophagy regulated by the NF-κB signaling pathways on hepatic stellate cell

3-Methyladenine (3-MA) is a selective type III phosphatidylinositol 3-kinase (PI3K) inhibitor and also blocks autophagosome formation. However, the effect of 3-MA in liver fibrosis has yet to be determined. Recent studies have demonstrated that autophagy is closely related to activation of hepatic s...

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Detalles Bibliográficos
Autores principales: Wang, Bingying, Yang, Huan, Fan, Yinyin, Yang, Yong, Cao, Wei, Jia, Yanwei, Cao, Ying, Sun, Kangyun, Pang, Zhi, Du, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746093/
https://www.ncbi.nlm.nih.gov/pubmed/29296191
http://dx.doi.org/10.18632/oncotarget.22539