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3-Methyladenine ameliorates liver fibrosis through autophagy regulated by the NF-κB signaling pathways on hepatic stellate cell
3-Methyladenine (3-MA) is a selective type III phosphatidylinositol 3-kinase (PI3K) inhibitor and also blocks autophagosome formation. However, the effect of 3-MA in liver fibrosis has yet to be determined. Recent studies have demonstrated that autophagy is closely related to activation of hepatic s...
Autores principales: | Wang, Bingying, Yang, Huan, Fan, Yinyin, Yang, Yong, Cao, Wei, Jia, Yanwei, Cao, Ying, Sun, Kangyun, Pang, Zhi, Du, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746093/ https://www.ncbi.nlm.nih.gov/pubmed/29296191 http://dx.doi.org/10.18632/oncotarget.22539 |
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