Autophagy flux inhibition, G2/M cell cycle arrest and apoptosis induction by ubenimex in glioma cell lines

This study aimed to investigate whether ubenimex could work as an anti-tumor drug alone in glioma cells and figure out the underlying potential mechanisms. Ubenimex is widely used as an adjunct therapy in multiple solid cancers. However, it is rarely used to treat glioblastoma. The function of ubeni...

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Detalles Bibliográficos
Autores principales: Han, Liping, Zhang, Yongfei, Liu, Shuai, Zhao, Qingwei, Liang, Xianhong, Ma, Zhiguo, Gupta, Prakash K., Zhao, Miaoqing, Wang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746103/
https://www.ncbi.nlm.nih.gov/pubmed/29296201
http://dx.doi.org/10.18632/oncotarget.22594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746103/
https://www.ncbi.nlm.nih.gov/pubmed/29296201
http://dx.doi.org/10.18632/oncotarget.22594

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