Sequencing of Lynch syndrome tumors reveals the importance of epigenetic alterations

Genomic instability and epigenetic aberrations are important classifiers of human tumors, yet, their interrelations are poorly understood. We used Lynch syndrome (LS) to address such relationships. Forty-five tumors (11 colorectal adenomas, 18 colorectal carcinomas, and 16 ovarian carcinomas) were p...

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Detalles Bibliográficos
Autores principales: Porkka, Noora, Valo, Satu, Nieminen, Taina T., Olkinuora, Alisa, Mäki-Nevala, Satu, Eldfors, Samuli, Peltomäki, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746122/
https://www.ncbi.nlm.nih.gov/pubmed/29296220
http://dx.doi.org/10.18632/oncotarget.22445

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746122/
https://www.ncbi.nlm.nih.gov/pubmed/29296220
http://dx.doi.org/10.18632/oncotarget.22445

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