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Adjustment of serum HE4 to reduced glomerular filtration and its use in biomarker-based prediction of deep myometrial invasion in endometrial cancer

BACKGROUND: We investigated the efficacy of circulating biomarkers together with histological grade and age to predict deep myometrial invasion (dMI) in endometrial cancer patients. METHODS: HE4ren was developed adjusting HE4 serum levels towards decreased glomerular filtration rate as quantified by...

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Detalles Bibliográficos
Autores principales: Chovanec, Josef, Selingerova, Iveta, Greplova, Kristina, Antonsen, Sofie Leisby, Nalezinska, Monika, Høgdall, Claus, Høgdall, Estrid, Søgaard-Andersen, Erik, Jochumsen, Kirsten M., Fabian, Pavel, Valik, Dalibor, Zdrazilova-Dubska, Lenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746137/
https://www.ncbi.nlm.nih.gov/pubmed/29296235
http://dx.doi.org/10.18632/oncotarget.22599