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Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity

Response to antidepressant treatment in major depressive disorder (MDD) cannot be predicted currently, leading to uncertainty in medication selection, increasing costs, and prolonged suffering for many patients. Despite tremendous efforts in identifying response-associated genes in large genome-wide...

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Detalles Bibliográficos
Autores principales: Carrillo-Roa, Tania, Labermaier, Christiana, Weber, Peter, Herzog, David P., Lareau, Caleb, Santarelli, Sara, Wagner, Klaus V., Rex-Haffner, Monika, Harbich, Daniela, Scharf, Sebastian H., Nemeroff, Charles B., Dunlop, Boadie W., Craighead, W. Edward, Mayberg, Helen S., Schmidt, Mathias V., Uhr, Manfred, Holsboer, Florian, Sillaber, Inge, Binder, Elisabeth B., Müller, Marianne B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746203/
https://www.ncbi.nlm.nih.gov/pubmed/29283992
http://dx.doi.org/10.1371/journal.pbio.2002690