Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS

Chimeric Antigen Receptor (CAR) T-cells have emerged as a powerful immunotherapy for various forms of cancer and show promise in treating HIV-1 infection. However, significant limitations are persistence and whether peripheral T cell-based products can respond to malignant or infected cells that may...

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Detalles Bibliográficos
Autores principales: Zhen, Anjie, Peterson, Christopher W., Carrillo, Mayra A., Reddy, Sowmya Somashekar, Youn, Cindy S., Lam, Brianna B., Chang, Nelson Y., Martin, Heather A., Rick, Jonathan W., Kim, Jennifer, Neel, Nick C., Rezek, Valerie K., Kamata, Masakazu, Chen, Irvin S. Y., Zack, Jerome A., Kiem, Hans-Peter, Kitchen, Scott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746250/
https://www.ncbi.nlm.nih.gov/pubmed/29284044
http://dx.doi.org/10.1371/journal.ppat.1006753

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746250/
https://www.ncbi.nlm.nih.gov/pubmed/29284044
http://dx.doi.org/10.1371/journal.ppat.1006753

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