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Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-κB pathway in ischemia/reperfusion injury after renal transplantation

Ischemia/reperfusion injury (IRI) commonly occurs in renal transplantation. Erythropoietin (EPO) exerts a protective effect in IRI. To investigate the underlying molecular mechanism, rat models of renal IRI were established and treated with EPO and/or lentivirus-mediated EPO-siRNA, the signal transd...

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Detalles Bibliográficos
Autores principales: Zhang, Jinhua, Zhao, Daqiang, Na, Ning, Li, Heng, Miao, Bin, Hong, Liangqing, Huang, Zhengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746301/
https://www.ncbi.nlm.nih.gov/pubmed/29115389
http://dx.doi.org/10.3892/ijmm.2017.3204