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Induced pluripotent stem cell-conditioned medium suppresses pulmonary fibroblast-to-myofibroblast differentiation via the inhibition of TGF-β1/Smad pathway

Therapeutic strategies based on stem cells have been shown to have potential in improving the condition of severe lung diseases. In this study, the suppressive effects of conditioned medium (CM) of induced pluripotent stem cells (iPSCs) on pulmonary fibroblast differentiation were investigated in a...

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Detalles Bibliográficos
Autores principales: Zhou, Yan, Zhang, Qiang, Gao, Yuan, Tan, Mingqi, Zheng, Rui, Zhao, Li, Zhang, Xiaoye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746308/
https://www.ncbi.nlm.nih.gov/pubmed/29115383
http://dx.doi.org/10.3892/ijmm.2017.3199