Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice

Renal tubulointerstitial fibrosis is characterized by sustained inflammation and excessive extracellular matrix (ECM) accumulation, leading to chronic kidney disease. Valproic acid (VPA) has anticancer activity through regulation of cell differentiation and apoptosis via inhibition of histone deacet...

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Detalles Bibliográficos
Autores principales: Nguyễn-Thanh, Tùng, Kim, Dal, Lee, Sik, Kim, Won, Park, Sung Kwang, Kang, Kyung Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746318/
https://www.ncbi.nlm.nih.gov/pubmed/29115561
http://dx.doi.org/10.3892/ijmm.2017.3218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746318/
https://www.ncbi.nlm.nih.gov/pubmed/29115561
http://dx.doi.org/10.3892/ijmm.2017.3218

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