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HIF-1α contributes to hypoxia adaptation of the naked mole rat

BACKGROUND/AIMS: Naked mole rats (NMRs) spend their lives in burrow systems containing very low levels of oxygen, indicating long-term hypoxic exposure, and suggesting that pathological changes caused by hypoxia are attenuated or absent in this hypoxia-tolerant species. The mechanisms underlying NMR...

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Detalles Bibliográficos
Autores principales: Xiao, Bang, Wang, Shiyong, Yang, Guoshi, Sun, Xiaoxi, Zhao, Shanmin, Lin, Lifang, Cheng, Jishuai, Yang, Wenjing, Cong, Wei, Sun, Wei, Kan, Guanghan, Cui, Shufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746355/
https://www.ncbi.nlm.nih.gov/pubmed/29299120
http://dx.doi.org/10.18632/oncotarget.22767