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Lewis y antigen promotes p27 degradation by regulating ubiquitin-proteasome activity

As a tumor-associated carbohydrate antigen, elevated expression of Lewis y promotes the malignant behaviors of tumor cells. Although our preliminary study showed that the increased expression of Lewis y antigen decreased the expression of cell cycle inhibitor protein p27, the relevant mechanism rema...

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Detalles Bibliográficos
Autores principales: Cai, Mingbo, Jin, Shan, Deng, Lu, Zhu, Liancheng, Hu, Zhenhua, Liu, Dawo, Liu, Juanjuan, Tan, Mingzi, Gao, Jian, Wang, Huimin, Lin, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746365/
https://www.ncbi.nlm.nih.gov/pubmed/29299130
http://dx.doi.org/10.18632/oncotarget.22617