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Saikosaponins A, C and D enhance liver-targeting effects of anticancer drugs by modulating drug transporters

Vinegar-baked Radix Bupleuri (VBRB) is clinically used to enhance the pharmacological activity of drugs used to treat liver diseases. Our previous study demonstrated that this effect is dependent on increased drug accumulation in the liver; however, the underlying mechanism remains unclear. We hypot...

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Detalles Bibliográficos
Autores principales: Feng, Limin, Liu, Lijuan, Zhao, Ya, Zhao, Ruizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746367/
https://www.ncbi.nlm.nih.gov/pubmed/29299132
http://dx.doi.org/10.18632/oncotarget.22639