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LINCRNA00273 promotes cancer metastasis and its G-Quadruplex promoter can serve as a novel target to inhibit cancer invasiveness

Discovery of anti-metastatic drugs is of immense clinical significance as metastasis is responsible for 90% of all cancer deaths. Here we report the inhibitory effect of a bis schiff base (M2) on cancer cell migration and invasion in vitro and in vivo. M2 has shown good solubility and permeability a...

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Detalles Bibliográficos
Autores principales: Jana, Samarjit, Jana, Jagannath, Patra, Kartick, Mondal, Soma, Bhat, Jyotsna, Sarkar, Arnab, Sengupta, Pallabi, Biswas, Anindya, Mukherjee, Meghomukta, Tripathi, Satya Prakash, Gangwal, Rahul, Hazra, Joyita, Sangamwar, Abhay T., Mukherjee, Gopeswar, Bhattacharjee, Shamee, Mandal, Deba Prasad, Chatterjee, Subhrangsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746379/
https://www.ncbi.nlm.nih.gov/pubmed/29299144
http://dx.doi.org/10.18632/oncotarget.22622