Inhibition of YAP function overcomes BRAF inhibitor resistance in melanoma cancer stem cells

Treating BRAF inhibitor-resistant melanoma is an important therapeutic goal. Thus, it is important to identify and target mechanisms of resistance to improve therapy. The YAP1 and TAZ proteins of the Hippo signaling pathway are important drivers of cancer cell survival, and are BRAF inhibitor resist...

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Detalles Bibliográficos
Autores principales: Fisher, Matthew L., Grun, Daniel, Adhikary, Gautam, Xu, Wen, Eckert, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746380/
https://www.ncbi.nlm.nih.gov/pubmed/29299145
http://dx.doi.org/10.18632/oncotarget.22628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746380/
https://www.ncbi.nlm.nih.gov/pubmed/29299145
http://dx.doi.org/10.18632/oncotarget.22628

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