FOXO3 induces ubiquitylation of AKT through MUL1 regulation

AKT (also known as protein kinase B, PKB) plays an important role in cell survival or tumor progression. For these reasons, AKT is an emerging target for cancer therapeutics. Previously our studies showed that mitochondrial E3 ubiquitin protein ligase 1 (MUL1, also known as MULAN/GIDE/MAPL) is suppr...

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Detalles Bibliográficos
Autores principales: Kim, Sun-Yong, Kim, Hyo Jeong, Byeon, Hyung Kwon, Kim, Dae Ho, Kim, Chul-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746397/
https://www.ncbi.nlm.nih.gov/pubmed/29299162
http://dx.doi.org/10.18632/oncotarget.22793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746397/
https://www.ncbi.nlm.nih.gov/pubmed/29299162
http://dx.doi.org/10.18632/oncotarget.22793

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