Ubiquitin Specific Peptidase 15 (USP15) suppresses glioblastoma cell growth via stabilization of HECTD1 E3 ligase attenuating WNT pathway activity

Expression based prediction of new genomic alterations in glioblastoma identified the de-ubiquitinase Ubiquitin Specific Peptidase 15 (USP15) as potential tumor suppressor gene associated with genomic deletions (11%). Ectopic expression of USP15 in glioblastoma cell-lines reduced colony formation an...

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Detalles Bibliográficos
Autores principales: Oikonomaki, Maria, Bady, Pierre, Hegi, Monika E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746398/
https://www.ncbi.nlm.nih.gov/pubmed/29299163
http://dx.doi.org/10.18632/oncotarget.22798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746398/
https://www.ncbi.nlm.nih.gov/pubmed/29299163
http://dx.doi.org/10.18632/oncotarget.22798

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