Melatonin up-regulates the expression of the GATA-4 transcription factor and increases testosterone secretion from Leydig cells through RORα signaling in an in vitro goat spermatogonial stem cell differentiation culture system

Because androgen function is regulated by its receptors, androgen-androgen receptor signaling is crucial for regulating spermatogenesis. Androgen is mainly testosterone secreted by testis. Based on the results of early studies in goats, the administration of melatonin over an extended period of time...

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Detalles Bibliográficos
Autores principales: Deng, Shou-Long, Zhang, Yan, Yu, Kun, Wang, Xiu-Xia, Chen, Su-Ren, Han, De-Ping, Cheng, C. Yan, Lian, Zheng-Xing, Liu, Yi-Xun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746406/
https://www.ncbi.nlm.nih.gov/pubmed/29299171
http://dx.doi.org/10.18632/oncotarget.22855

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746406/
https://www.ncbi.nlm.nih.gov/pubmed/29299171
http://dx.doi.org/10.18632/oncotarget.22855

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