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Using single-cell multiple omics approaches to resolve tumor heterogeneity

It has become increasingly clear that both normal and cancer tissues are composed of heterogeneous populations. Genetic variation can be attributed to the downstream effects of inherited mutations, environmental factors, or inaccurately resolved errors in transcription and replication. When lesions...

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Detalles Bibliográficos
Autores principales: Ortega, Michael A., Poirion, Olivier, Zhu, Xun, Huang, Sijia, Wolfgruber, Thomas K., Sebra, Robert, Garmire, Lana X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746494/
https://www.ncbi.nlm.nih.gov/pubmed/29285690
http://dx.doi.org/10.1186/s40169-017-0177-y