Cell-to-cell Transmission of Polyglutamine Aggregates in C. elegans

Huntington disease (HD) is an inherited neurodegenerative disorder characterized by motor and cognitive dysfunction caused by expansion of polyglutamine (polyQ) repeat in exon 1 of huntingtin (HTT). In patients, the number of glutamine residues in polyQ tracts are over 35, and it is correlated with...

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Detalles Bibliográficos
Autores principales: Kim, Dong-Kyu, Cho, Kyu-Won, Ahn, Woo Jung, Perez-Acuña, Dayana, Jeong, Hyunsu, Lee, He-Jin, Lee, Seung-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746497/
https://www.ncbi.nlm.nih.gov/pubmed/29302199
http://dx.doi.org/10.5607/en.2017.26.6.321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746497/
https://www.ncbi.nlm.nih.gov/pubmed/29302199
http://dx.doi.org/10.5607/en.2017.26.6.321

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