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Histone deacetylase inhibition attenuates hepatic steatosis in rats with experimental Cushing's syndrome

Cushing's syndrome (CS) is a collection of symptoms caused by prolonged exposure to excess cortisol. Chronically elevated glucocorticoid (GC) levels contribute to hepatic steatosis. We hypothesized that histone deacetylase inhibitors (HDACi) could attenuate hepatic steatosis through glucocortic...

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Detalles Bibliográficos
Autores principales: Kim, Mina, Lee, Hae-Ahm, Cho, Hyun-Min, Kang, Seol-Hee, Lee, Eunjo, Kim, In Kyeom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746509/
https://www.ncbi.nlm.nih.gov/pubmed/29302209
http://dx.doi.org/10.4196/kjpp.2018.22.1.23