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Epigenetic modification of α-N-acetylgalactosaminidase enhances cisplatin resistance in ovarian cancer

Although cisplatin is one of the most effective antitumor drugs for ovarian cancer, the emergence of chemoresistance to cisplatin in over 80% of initially responsive patients is a major barrier to successful therapy. The precise mechanisms underlying the development of cisplatin resistance are not f...

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Detalles Bibliográficos
Autores principales: Ha, Ye-Na, Sung, Hye Youn, Yang, San-Duk, Chae, Yun Ju, Ju, Woong, Ahn, Jung-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746511/
https://www.ncbi.nlm.nih.gov/pubmed/29302211
http://dx.doi.org/10.4196/kjpp.2018.22.1.43