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Measuring in vivo responses to endogenous and exogenous oxidative stress using a novel haem oxygenase 1 reporter mouse

KEY POINTS: Haem oxygenase 1 (Hmox1) is a cytoprotective enzyme with anti‐inflammatory and anti‐oxidant properties that is induced in response to multiple noxious environmental stimuli and disease states. Tools to enable its expression to be monitored in vivo have been unavailable until now. In a ne...

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Detalles Bibliográficos
Autores principales: McMahon, Michael, Ding, Shaohong, Acosta‐Jimenez, Lourdes P., Frangova, Tania G., Henderson, Colin J., Wolf, C. Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746521/
https://www.ncbi.nlm.nih.gov/pubmed/29086419
http://dx.doi.org/10.1113/JP274915