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Adipose tissue: a new target for electroporation-enhanced DNA vaccines

DNA vaccines delivered using electroporation (EP) have had clinical success, but these EP methods generally utilize invasive needle electrodes. Here, we demonstrate the delivery and immunogenicity of a DNA vaccine into subcutaneous adipose tissue cells using noninvasive EP. Using finite element anal...

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Detalles Bibliográficos
Autores principales: Fisher, P D, Brambila, C J, McCoy, J R, Kiosses, W B, Mendoza, J M, Oh, J, Yung, B S, Schultheis, K, Smith, T R F, Broderick, K E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746593/
https://www.ncbi.nlm.nih.gov/pubmed/29106403
http://dx.doi.org/10.1038/gt.2017.96