Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina

There is much debate on the adeno-associated virus (AAV) serotype that best targets specific retinal cell types and the route of surgical delivery—intravitreal or subretinal. This study compared three of the most efficacious AAV vectors known to date in a mouse model of retinal degeneration (rd1 mou...

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Detalles Bibliográficos
Autores principales: Hickey, D G, Edwards, T L, Barnard, A R, Singh, M S, de Silva, S R, McClements, M E, Flannery, J G, Hankins, M W, MacLaren, R E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746594/
https://www.ncbi.nlm.nih.gov/pubmed/28872643
http://dx.doi.org/10.1038/gt.2017.85

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746594/
https://www.ncbi.nlm.nih.gov/pubmed/28872643
http://dx.doi.org/10.1038/gt.2017.85

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