Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle

MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (Pol II). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma cells. The analysis shows that N-MYC forms complexes with...

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Detalles Bibliográficos
Autores principales: Büchel, Gabriele, Carstensen, Anne, Mak, Ka-Yan, Roeschert, Isabelle, Leen, Eoin, Sumara, Olga, Hofstetter, Julia, Herold, Steffi, Kalb, Jacqueline, Baluapuri, Apoorva, Poon, Evon, Kwok, Colin, Chesler, Louis, Maric, Hans Michael, Rickman, David S., Wolf, Elmar, Bayliss, Richard, Walz, Susanne, Eilers, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746598/
https://www.ncbi.nlm.nih.gov/pubmed/29262328
http://dx.doi.org/10.1016/j.celrep.2017.11.090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746598/
https://www.ncbi.nlm.nih.gov/pubmed/29262328
http://dx.doi.org/10.1016/j.celrep.2017.11.090

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