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PureCLIP: capturing target-specific protein–RNA interaction footprints from single-nucleotide CLIP-seq data
The iCLIP and eCLIP techniques facilitate the detection of protein–RNA interaction sites at high resolution, based on diagnostic events at crosslink sites. However, previous methods do not explicitly model the specifics of iCLIP and eCLIP truncation patterns and possible biases. We developed PureCLI...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746957/ https://www.ncbi.nlm.nih.gov/pubmed/29284540 http://dx.doi.org/10.1186/s13059-017-1364-2 |