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Xeno- and feeder-free differentiation of human pluripotent stem cells to two distinct ocular epithelial cell types using simple modifications of one method

BACKGROUND: Human pluripotent stem cells (hPSCs) provide a promising cell source for ocular cell replacement therapy, but often lack standardized and xenogeneic-free culture and differentiation protocols. We aimed to develop a xeno- and feeder cell-free culture system for undifferentiated hPSCs alon...

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Detalles Bibliográficos
Autores principales: Hongisto, Heidi, Ilmarinen, Tanja, Vattulainen, Meri, Mikhailova, Alexandra, Skottman, Heli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747074/
https://www.ncbi.nlm.nih.gov/pubmed/29284513
http://dx.doi.org/10.1186/s13287-017-0738-4