Bidirectional transcription initiation marks accessible chromatin and is not specific to enhancers

BACKGROUND: Enhancers are modular regulatory elements that are central to the spatial and temporal regulation of gene expression. Bidirectional transcription initiating at enhancers has been proposed to mark active enhancers and as such has been utilized to experimentally identify active enhancers d...

Descripción completa

Detalles Bibliográficos
Autores principales: Young, Robert S., Kumar, Yatendra, Bickmore, Wendy A., Taylor, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747114/
https://www.ncbi.nlm.nih.gov/pubmed/29284524
http://dx.doi.org/10.1186/s13059-017-1379-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747114/
https://www.ncbi.nlm.nih.gov/pubmed/29284524
http://dx.doi.org/10.1186/s13059-017-1379-8

Ejemplares similares