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Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells
BACKGROUND: Glioma stem cells (GSCs) contribute to tumor recurrence and drug resistance. This study characterizes the tumorigenesis of CD133(+) cells and their sensitivity to pharmacological inhibition. METHODS: GSCs from human U87 and rat C6 glioblastoma cell lines were isolated via magnetic cell s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747127/ https://www.ncbi.nlm.nih.gov/pubmed/29284440 http://dx.doi.org/10.1186/s12885-017-3924-y |