Cargando…

Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells

BACKGROUND: Glioma stem cells (GSCs) contribute to tumor recurrence and drug resistance. This study characterizes the tumorigenesis of CD133(+) cells and their sensitivity to pharmacological inhibition. METHODS: GSCs from human U87 and rat C6 glioblastoma cell lines were isolated via magnetic cell s...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Chia-Hsin, Liu, Wei-Ting, Hung, Hui-Chi, Gean, Chia-Yu, Tsai, Hong-Ming, Su, Chun-Lin, Gean, Po-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747127/
https://www.ncbi.nlm.nih.gov/pubmed/29284440
http://dx.doi.org/10.1186/s12885-017-3924-y