mTOR inhibition improves the immunomodulatory properties of human bone marrow mesenchymal stem cells by inducing COX-2 and PGE(2)

BACKGROUND: Bone marrow mesenchymal stem cells (MSCs) are promising candidates for the treatment of various inflammatory disorders due to their profound immunomodulatory properties. However, the immunosuppressive capacity of MSCs needs activation by an inflammatory microenvironment, which may negati...

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Detalles Bibliográficos
Autores principales: Wang, Binsheng, Lin, Yu, Hu, Yongxian, Shan, Wei, Liu, Senquan, Xu, Yulin, Zhang, Hao, Cai, Shuyang, Yu, Xiaohong, Cai, Zhen, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747167/
https://www.ncbi.nlm.nih.gov/pubmed/29287601
http://dx.doi.org/10.1186/s13287-017-0744-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747167/
https://www.ncbi.nlm.nih.gov/pubmed/29287601
http://dx.doi.org/10.1186/s13287-017-0744-6

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