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DE-kupl: exhaustive capture of biological variation in RNA-seq data through k-mer decomposition
We introduce a k-mer-based computational protocol, DE-kupl, for capturing local RNA variation in a set of RNA-seq libraries, independently of a reference genome or transcriptome. DE-kupl extracts all k-mers with differential abundance directly from the raw data files. This enables the retrieval of v...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747171/ https://www.ncbi.nlm.nih.gov/pubmed/29284518 http://dx.doi.org/10.1186/s13059-017-1372-2 |