DE-kupl: exhaustive capture of biological variation in RNA-seq data through k-mer decomposition

We introduce a k-mer-based computational protocol, DE-kupl, for capturing local RNA variation in a set of RNA-seq libraries, independently of a reference genome or transcriptome. DE-kupl extracts all k-mers with differential abundance directly from the raw data files. This enables the retrieval of v...

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Detalles Bibliográficos
Autores principales: Audoux, Jérôme, Philippe, Nicolas, Chikhi, Rayan, Salson, Mikaël, Gallopin, Mélina, Gabriel, Marc, Le Coz, Jérémy, Drouineau, Emilie, Commes, Thérèse, Gautheret, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747171/
https://www.ncbi.nlm.nih.gov/pubmed/29284518
http://dx.doi.org/10.1186/s13059-017-1372-2

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