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Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR

Cytosine methylation is an important DNA epigenetic modification. In vertebrates, methylation occurs at CpG sites, which are dinucleotides where a cytosine is immediately followed by a guanine in the DNA sequence from 5' to 3'. When located in the promoter region of a gene, DNA methylation...

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Detalles Bibliográficos
Autores principales: Chen, Yunshun, Pal, Bhupinder, Visvader, Jane E., Smyth, Gordon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747346/
https://www.ncbi.nlm.nih.gov/pubmed/29333247
http://dx.doi.org/10.12688/f1000research.13196.2