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Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR
Cytosine methylation is an important DNA epigenetic modification. In vertebrates, methylation occurs at CpG sites, which are dinucleotides where a cytosine is immediately followed by a guanine in the DNA sequence from 5' to 3'. When located in the promoter region of a gene, DNA methylation...
Autores principales: | Chen, Yunshun, Pal, Bhupinder, Visvader, Jane E., Smyth, Gordon K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747346/ https://www.ncbi.nlm.nih.gov/pubmed/29333247 http://dx.doi.org/10.12688/f1000research.13196.2 |
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