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Asymmetry between Activation and Deactivation during a Transcriptional Pulse

Transcription in eukaryotic cells occurs in gene-specific bursts or pulses of activity. Recent studies identified a spectrum of transcriptionally active “on-states,” interspersed with periods of inactivity, but these “off-states” and the process of transcriptional deactivation are poorly understood....

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Detalles Bibliográficos
Autores principales: Dunham, Lee S.S., Momiji, Hiroshi, Harper, Claire V., Downton, Polly J., Hey, Kirsty, McNamara, Anne, Featherstone, Karen, Spiller, David G., Rand, David A., Finkenstädt, Bärbel, White, Michael R.H., Davis, Julian R.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747351/
https://www.ncbi.nlm.nih.gov/pubmed/29153839
http://dx.doi.org/10.1016/j.cels.2017.10.013