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Asymmetry between Activation and Deactivation during a Transcriptional Pulse
Transcription in eukaryotic cells occurs in gene-specific bursts or pulses of activity. Recent studies identified a spectrum of transcriptionally active “on-states,” interspersed with periods of inactivity, but these “off-states” and the process of transcriptional deactivation are poorly understood....
Autores principales: | Dunham, Lee S.S., Momiji, Hiroshi, Harper, Claire V., Downton, Polly J., Hey, Kirsty, McNamara, Anne, Featherstone, Karen, Spiller, David G., Rand, David A., Finkenstädt, Bärbel, White, Michael R.H., Davis, Julian R.E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747351/ https://www.ncbi.nlm.nih.gov/pubmed/29153839 http://dx.doi.org/10.1016/j.cels.2017.10.013 |
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