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Novel IRF-1 Mutations in a Small Cohort of Leukaemia Patients From Saudi Arabia

Involvement of the Interferon Regulatory Factor 1 (IRF-1) gene in regulation of cell differentiation and proliferation made it a potential target in cancer research. IRF-1 acts as a tumor suppressor gene, and is inactivated in chronic (CML) and non-chronic myelogenous leukemia (non-CML). In the ligh...

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Detalles Bibliográficos
Autores principales: Alsamman, Khaldoon, Zhang, Xiuli, Vatte, Chittibabu, Hamad, Mohammad Al, El-Masry, Omar S, Owaidah, Amani Y, Alzahrani, Faisal, Lin, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747406/
https://www.ncbi.nlm.nih.gov/pubmed/29072416
http://dx.doi.org/10.22034/APJCP.2017.18.10.2795