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Dose-Duration Reciprocity for G protein activation: Modulation of kinase to substrate ratio alters cell signaling

In animal cells, activation of heterotrimeric G protein signaling generally occurs when the system’s cognate signal exceeds a threshold, whereas in plant cells, both the amount and the exposure time of at least one signal, D-glucose, are used toward activation. This unusual signaling property called...

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Detalles Bibliográficos
Autores principales: Liao, Kang-Ling, Melvin, Charles E., Sozzani, Rosangela, Jones, Roger D., Elston, Timothy C., Jones, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747438/
https://www.ncbi.nlm.nih.gov/pubmed/29287086
http://dx.doi.org/10.1371/journal.pone.0190000